{"id":2453,"date":"2024-02-02T15:26:55","date_gmt":"2024-02-02T15:26:55","guid":{"rendered":"http:\/\/aqpbiocenter.com.vn\/?p=2453"},"modified":"2024-02-20T10:14:20","modified_gmt":"2024-02-20T10:14:20","slug":"nghien-cuu-tuong-duong-sinh-hoc-va-sinh-kha-dung-la-gi","status":"publish","type":"post","link":"https:\/\/aqpbiocenter.com.vn\/en\/nghien-cuu-tuong-duong-sinh-hoc-va-sinh-kha-dung-la-gi\/","title":{"rendered":"Nghi\u00ean c\u1ee9u t\u01b0\u01a1ng \u0111\u01b0\u01a1ng sinh h\u1ecdc v\u00e0 sinh kh\u1ea3 d\u1ee5ng l\u00e0 g\u00ec?"},"content":{"rendered":"<p>T\u01b0\u01a1ng \u0111\u01b0\u01a1ng sinh h\u1ecdc v\u00e0 sinh kh\u1ea3 d\u1ee5ng: \u0110o l\u01b0\u1eddng v\u00e0 so s\u00e1nh l\u01b0u th\u00f4ng thu\u1ed1c trong h\u1ec7 tu\u1ea7n ho\u00e0n.<\/p>\n<p>Sinh kh\u1ea3 d\u1ee5ng c\u1ee7a thu\u1ed1c l\u00e0 n\u1ed3ng \u0111\u1ed9 c\u1ee7a h\u1ee3p ch\u1ea5t thu\u1ed1c trong h\u1ec7 tu\u1ea7n ho\u00e0n ho\u1eb7c t\u1ea1i v\u1ecb tr\u00ed t\u00e1c d\u1ee5ng.<\/p>\n<p>\u0110a ph\u1ea7n c\u00e1c lo\u1ea1i thu\u1ed1c ho\u1eb7c d\u01b0\u1ee3c ph\u1ea9m \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng \u0111\u1ec1u \u0111i v\u00e0o h\u1ec7 tu\u1ea7n ho\u00e0n qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. C\u00e1c h\u1ee3p ch\u1ea5t thu\u1ed1c n\u00e0y sau \u0111\u00f3 \u0111i v\u00e0o v\u1ecb tr\u00ed t\u00e1c d\u1ee5ng th\u00f4ng qua h\u1ec7 tu\u1ea7n ho\u00e0n. Sinh kh\u1ea3 d\u1ee5ng c\u1ee7a thu\u1ed1c \u0111\u01b0\u1ee3c \u0111o b\u1eb1ng c\u00e1ch \u0111\u00e1nh gi\u00e1 n\u1ed3ng \u0111\u1ed9 ho\u1ea1t ch\u1ea5t (API) c\u1ee7a thu\u1ed1c v\u00e0 b\u1ea5t k\u1ef3 ch\u1ea5t chuy\u1ec3n h\u00f3a n\u00e0o trong huy\u1ebft t\u01b0\u01a1ng ho\u1eb7c huy\u1ebft thanh. N\u1ed3ng \u0111\u1ed9 API c\u0169ng gi\u00fap x\u00e1c \u0111\u1ecbnh s\u1ef1 gi\u1ea3i ph\u00f3ng th\u00e0nh ph\u1ea7n ho\u1ea1t ch\u1ea5t t\u1eeb c\u00e1c h\u1ee3p ch\u1ea5t thu\u1ed1c c\u00f9ng v\u1edbi s\u1ef1 h\u1ea5p thu, ph\u00e2n ph\u1ed1i, chuy\u1ec3n h\u00f3a v\u00e0 b\u00e0i ti\u1ebft c\u1ee7a n\u00f3.<\/p>\n<p>Ba bi\u1ebfn s\u1ed1 ch\u00ednh c\u1ee7a nghi\u00ean c\u1ee9u d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 sinh kh\u1ea3 d\u1ee5ng c\u1ee7a thu\u1ed1c l\u00e0 i) n\u1ed3ng \u0111\u1ed9 thu\u1ed1c t\u1ed1i \u0111a trong h\u1ec7 th\u1ed1ng tu\u1ea7n ho\u00e0n (Cmax), ii) th\u1eddi gian \u0111\u1ec3 thu\u1ed1c \u0111\u1ea1t \u0111\u01b0\u1ee3c n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a trong h\u1ec7 tu\u1ea7n ho\u00e0n (Tmax) v\u00e0 iii) di\u1ec7n t\u00edch d\u01b0\u1edbi \u0111\u01b0\u1eddng cong bi\u1ec3u di\u1ec5n n\u1ed3ng \u0111\u1ed9 thu\u1ed1c theo th\u1eddi gian (AUC).<\/p>\n<p>N\u1ebfu sinh kh\u1ea3 d\u1ee5ng c\u1ee7a hai s\u1ea3n ph\u1ea9m thu\u1ed1c t\u01b0\u01a1ng \u0111\u01b0\u01a1ng nhau th\u00ec g\u1ecdi l\u00e0 t\u01b0\u01a1ng \u0111\u01b0\u01a1ng sinh h\u1ecdc.<\/p>\n<p>Hi\u1ec7n t\u1ea1i, C\u00f4ng ty c\u1ed5 ph\u1ea7n nghi\u00ean c\u1ee9u v\u00e0 ki\u1ec3m nghi\u1ec7m thu\u1ed1c AQP v\u1edbi h\u01a1n 14 n\u0103m kinh nghi\u1ec7m ho\u1ea1t \u0111\u1ed9ng trong l\u0129nh v\u1ef1c cung c\u1ea5p d\u1ecbch v\u1ee5 th\u1eed t\u01b0\u01a1ng \u0111\u01b0\u01a1ng sinh h\u1ecdc lu\u00f4n s\u1eb5n s\u00e0ng \u0111\u00e1p \u1ee9ng m\u1ecdi nhu c\u1ea7u c\u1ee7a kh\u00e1ch h\u00e0ng.<\/p>\n<p><strong><sup>(*)<\/sup><\/strong><strong> T\u00e0i li\u1ec7u tham kh\u1ea3o<\/strong><\/p>\n<blockquote class=\"wp-embedded-content\" data-secret=\"QDXPqtnCbL\"><p><a href=\"https:\/\/www.nebiolab.com\/bioequivalence-bioavailability-drug-studies\/\">Bioequivalence and Bioavailability Study<\/a><\/p><\/blockquote>\n<p><iframe class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;Bioequivalence and Bioavailability Study&#8221; &#8212; NorthEast BioLab\" src=\"https:\/\/www.nebiolab.com\/bioequivalence-bioavailability-drug-studies\/embed\/#?secret=OF99AIMVQY#?secret=QDXPqtnCbL\" data-secret=\"QDXPqtnCbL\" width=\"600\" height=\"338\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n","protected":false},"excerpt":{"rendered":"<p>T\u01b0\u01a1ng \u0111\u01b0\u01a1ng sinh h\u1ecdc v\u00e0 sinh kh\u1ea3 d\u1ee5ng: \u0110o l\u01b0\u1eddng v\u00e0 so s\u00e1nh l\u01b0u th\u00f4ng thu\u1ed1c trong h\u1ec7 tu\u1ea7n ho\u00e0n.<\/p>\n","protected":false},"author":1,"featured_media":2466,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[32],"tags":[],"translation":{"provider":"WPGlobus","version":"2.6.6","language":"en","enabled_languages":["vi","en"],"languages":{"vi":{"title":true,"content":true,"excerpt":false},"en":{"title":false,"content":false,"excerpt":false}}},"_links":{"self":[{"href":"https:\/\/aqpbiocenter.com.vn\/en\/wp-json\/wp\/v2\/posts\/2453"}],"collection":[{"href":"https:\/\/aqpbiocenter.com.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/aqpbiocenter.com.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/aqpbiocenter.com.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/aqpbiocenter.com.vn\/en\/wp-json\/wp\/v2\/comments?post=2453"}],"version-history":[{"count":2,"href":"https:\/\/aqpbiocenter.com.vn\/en\/wp-json\/wp\/v2\/posts\/2453\/revisions"}],"predecessor-version":[{"id":2457,"href":"https:\/\/aqpbiocenter.com.vn\/en\/wp-json\/wp\/v2\/posts\/2453\/revisions\/2457"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/aqpbiocenter.com.vn\/en\/wp-json\/wp\/v2\/media\/2466"}],"wp:attachment":[{"href":"https:\/\/aqpbiocenter.com.vn\/en\/wp-json\/wp\/v2\/media?parent=2453"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/aqpbiocenter.com.vn\/en\/wp-json\/wp\/v2\/categories?post=2453"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/aqpbiocenter.com.vn\/en\/wp-json\/wp\/v2\/tags?post=2453"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}